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Mutation. Either exchanging a Purine with another Purine, Pyrimidin with another Pyrimidin, or completely exchanging a Purine with a Pyrimidin or vice versa. Point- or Frameshift-Mutation.

Answer: Change in a single nitrogen base in the DNA sequence will not have any significant effect on the organism.

Explanation:

This is known as point mutation and it does not have any significant change in the protein and it is least harmful type of DNA mutation.

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